Retatrutide

Accelerating

Retatrutide appears in 198 indexed publications going back to 2022, including 90 in the past twelve months. 34 registered trials appear on ClinicalTrials.gov, 6 with Australian sites.

198

Indexed publications

Past 12 months, against 59 the year before

Registered clinical trials

35,065

Monthly readers on Wikipedia, down 11%

Research Activity

Publication history

How much work has been indexed each year, from Europe PMC. Momentum is measured over a trailing twelve months rather than calendar years, so a partial current year never reads as a decline.

20152026

Publications per year. The final bar is the current year, still in progress.

Indexed publications per year
2015	0
2016	0
2017	0
2018	0
2019	0
2020	0
2021	0
2022	2
2023	16
2024	41
2025	58
2026	81

Public Attention

Who is looking it up

Monthly readers of the Retatrutide article on English Wikipedia. An independent measure of curiosity, which often moves quite differently from the evidence.

2025-092026-08

Clinical Trials

The registered pipeline

Early Phase 1

Phase 1

Phase 2

Phase 3

Phase 4

6 trials have a registered Australian site.

Phase distribution across the most recently updated registered trials.

Recruiting·Phase 3Australian site
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Eli Lilly and Company · estimated completion 2030-08
Active, not recruiting·Phase 3Australian site
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
Eli Lilly and Company · estimated completion 2029-02
Completed·Phase 3Australian site
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
Eli Lilly and Company · completed 2026-04-06
AVAILABLE
Pre-approval Expanded Access of Retatrutide (LY3437943)
Eli Lilly and Company
Active, not recruiting·Phase 3
Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
Eli Lilly and Company · estimated completion 2026-10
Active, not recruiting·Phase 3
A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity
Eli Lilly and Company · estimated completion 2026-11

References

Most recent work

The newest indexed records mentioning Retatrutide, listed by publication date. Titles are shown as published and link to their source. Inclusion here is a record of what exists, not a judgement of what it shows.

2026-07-21·Journal of chromatography. A
Development and validation of a multiplexed LC-HRMS method for nine GLP-1 receptor agonists and its pharmaceutical application
Tong LH, Leung KK, Hung CT. et al.
2026-07-01·Behavioural brain research
Effects of retatrutide on learning and memory in streptozotocin-induced male diabetic rats
Keskin U, Altın E, Kara MK et al.
2026-09-01·Diabetes & metabolism journal
Beyond Fat Loss: Addressing the Sarcopenia Challenge of Incretin-Based Therapies
Kim JY, Kim NH. et al.
2026-09-10·Canadian journal of physiology and pharmacology
CARDIOVASCULAR EFFECTS OF INCRETIN RECEPTOR AGONISTS: BEYOND GLYCEMIC CONTROL
Ravic M, Srejovic IM, Milosavljevic I et al.
2026-09-03·Current medical research and opinion
From insulin resistance to incretin receptor agonism in the prevention of type 2 diabetes mellitus in obese individuals
Teofilović B, Trkulja J, Grujić-Letić N et al.
2026-09-02·Indian journal of pharmacology
Pharmacological management of obesity: Current landscape and emerging therapies
Atal S, Agrawal C, Gupta R et al.
2026-09-01·Kidney research and clinical practice
Incretin-based therapies in diabetic kidney disease: toward integrated cardio-kidney-metabolic disease modification
Kim Y, Lee EY, Korean Diabetic Kidney Disease Study Group. et al.
2026-09-01·Annals of internal medicine
Efficacy and Safety of Glucagon-like Peptide-1 Receptor Agonists and Co-agonists for Weight Loss Among Adults Without Diabetes : An Updated Systematic Review
Moiz A, Filion KB, Samuels AE et al.

In the Catalogue

Retatrutide available from Polaris Research

Supplied as research materials for laboratory use. Free express delivery Australia wide.

Sources

Publication data from Europe PMC. Clinical trial data from ClinicalTrials.gov, U.S. National Library of Medicine. Public attention from Wikimedia pageview data. Evidence grades from reptides.co. We report counts and dates from these sources and link every record to its origin, we do not summarise findings. Last synced 2026-09-13.