Retatrutide

Accelerating

Retatrutide appears in 230 indexed publications going back to 2022, including 114 in the past twelve months. 34 registered trials appear on ClinicalTrials.gov, 6 with Australian sites.

230

Indexed publications

114

Past 12 months, against 59 the year before

Registered clinical trials

35,139

Monthly readers on Wikipedia, up 0%

Research Activity

Publication history

How much work has been indexed each year, from Europe PMC. Momentum is measured over a trailing twelve months rather than calendar years, so a partial current year never reads as a decline.

20152026

Publications per year. The final bar is the current year, still in progress.

Indexed publications per year
2015	0
2016	0
2017	0
2018	0
2019	0
2020	0
2021	0
2022	2
2023	16
2024	40
2025	58
2026	114

Public Attention

Who is looking it up

Monthly readers of the Retatrutide article on English Wikipedia. An independent measure of curiosity, which often moves quite differently from the evidence.

2025-102026-09

Clinical Trials

The registered pipeline

Early Phase 1

Phase 1

Phase 2

Phase 3

Phase 4

6 trials have a registered Australian site.

Phase distribution across the most recently updated registered trials.

Active, not recruiting·Phase 1
A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes Mellitus
Eli Lilly and Company · estimated completion 2027-01
Active, not recruiting·Phase 3
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain
Eli Lilly and Company · estimated completion 2027-09
AVAILABLE
Pre-approval Expanded Access of Retatrutide (LY3437943)
Eli Lilly and Company
Completed·Phase 3Australian site
A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease
Eli Lilly and Company · completed 2026-04-16
Completed·Phase 3Australian site
A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight
Eli Lilly and Company · completed 2026-06-16
Completed·Phase 1
A Study to Investigate the Response of Participants With Type 2 Diabetes Mellitus on Once-Weekly Retatrutide to Hypoglycemia
Eli Lilly and Company · completed 2026-05-04

References

Most recent work

The newest indexed records mentioning Retatrutide, listed by publication date. Titles are shown as published and link to their source. Inclusion here is a record of what exists, not a judgement of what it shows.

2026-10-12·Journal of diabetes and metabolic disorders
The pharmacotherapy for pediatric obesity: insights and challenges from adult weight-loss medications
Chen Z, Zhou Y, Li G et al.
2026-12-01·Rapid communications in mass spectrometry : RCM
Detection and Excretion Profile of Retatrutide in Human Plasma and Urine by LC-HRMS: Implications for Antidoping Analysis
Carneiro GRA, da Costa Nunes IK, Dos Santos Cardoso GR et al.
2026-08-17·Diabetes, obesity & metabolism
Retatrutide-Associated Improvements in Cardiovascular Risk Biomarkers in Adults With Obesity With or Without Type 2 Diabetes
Ruotolo G, Harris C, Lin Y et al.
2024-10-08·Cardiology in review
The First Triple Agonist for Antiobesity: Retatrutide
Tetelbaun L, Mullally JA, Frishman WH. et al.
2026-10-22·Reviews in endocrine & metabolic disorders
Glucose-dependent insulinotropic polypeptide (GIP) signaling in visceral and subcutaneous adipose tissue: implications for obesity and metabolic disease-a narrative review with a structured literature search
Smarkusz-Zarzecka J, Radziszewska M, Gofron KK et al.
2026-10-21·The New England journal of medicine
Retatrutide Once Weekly for Treatment of Obstructive Sleep Apnea
Grunstein RR, Somers VK, Azarbarzin A et al.
2026-10-15·Journal of molecular histology
Retatrutide treatment in streptozotocin-induced diabetic rats: renal inflammatory cytokines, HIF‑1α expression, and histopathological injury profile
Keskin U, Altın E, Özatik FY et al.
2026-10-01·JAMA network open
Self-Reported Adverse Effects Among Social Media Users Taking Nonapproved Retatrutide
Sehgal NKR, Tronieri JS, Rader B et al.

In the Catalogue

Retatrutide available from Polaris Research

Supplied as research materials for laboratory use. Free express delivery Australia wide.

Sources

Publication data from Europe PMC. Clinical trial data from ClinicalTrials.gov, U.S. National Library of Medicine. Public attention from Wikimedia pageview data. Evidence grades from reptides.co. We report counts and dates from these sources and link every record to its origin, we do not summarise findings. Last synced 2026-10-25.