The peptide research register

Each compound has a fixed, hand written search expression, version pinned so a change from one week to the next reflects new research rather than a changed question. Publication counts come from Europe PMC using a fielded title, abstract and keyword search, because an unfielded search matches full text and inflates a count several times over. Trial counts come from the ClinicalTrials.gov v2 API with term expansion switched off, because its fuzzy default returns studies that have nothing to do with the compound.

Momentum compares a trailing twelve months against the twelve before it, never calendar years, since a partial current year would always read as a decline. Where a name is ambiguous, such as SS-31 or KPV, the query carries a context filter and the page says so. Where a compound names ubiquitous biochemistry, such as NAD+ or glutathione, the count describes an entire field and is labelled accordingly.

A compound with little research is reported plainly rather than hidden. Most of these peptides have no remaining composition of matter patent, so there is no exclusivity, no commercial sponsor, and therefore no funded clinical programme. A thin file is usually a fact about the economics of drug development, not about the molecule.