Reconstitution
Bacteriostatic Water 3mL
$10
Laboratory research material only. Not for human or animal consumption.Laboratory research material only. For qualified in-vitro and laboratory research use. Not for human or animal consumption, injection, or therapeutic use. Not a medicine, supplement, or cosmetic.
Weight & Metabolism · 10mg
MOTS-c 10mg
CAS 1627580-64-6
$109
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1
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Sealed Under Argon
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MOTS-c, also written MOTSc or MOTS c, is a mitochondrial-derived peptide (encoded within mitochondrial DNA) studied for metabolic flexibility, insulin-sensitivity, mitochondrial, and exercise-adaptation research. It belongs to a class of peptides encoded by the mitochondrial genome rather than the nucleus, and it is studied for how it engages the metabolic and exercise-adaptation pathways associated with that origin. The 10mg vial is the standard reference format.In preclinical and in-vitro research, MOTS-c is investigated for its role in metabolic-flexibility, insulin-signalling, and exercise-adaptation models, with research interest in how a mitochondrially encoded peptide communicates with the rest of the cell. Its mitochondrial-DNA origin is the defining research characteristic and the reason it is studied as a distinct metabolic-signalling reference.MOTS-c sits in the metabolism family and the wider energy-and-longevity range; researchers studying mitochondrial and metabolic pathways often look at it alongside NAD+ and SS-31. Our library covers the cellular-energy pathways these compounds are studied for. The 10mg vial here is the clean single-compound reference for MOTS-c.Every 10mg vial ships lyophilised with an independently verified batch certificate at a guaranteed floor of ≥98% purity, verifiable on the batch verification page using the batch number on the label. Reconstitute with bacteriostatic water: add it slowly down the inside wall of the vial, swirl gently, and never shake. Store the unopened vial at 2 to 8°C; refrigerate once reconstituted and do not refreeze. CAS reference 1627580-64-6.Buying MOTS-c in Australia is domestic: free Australia Post Express shipping to every state and territory, no minimum spend, dispatch from within Australia, and tracking on every parcel. Checkout accepts card, PayPal, or PayID, each vial is sealed under argon, and a 24-hour reservation holds your stock from order. Supplied strictly as a research material for lawful laboratory and in-vitro use, not for human or veterinary consumption.
Formal Name
MOTS-c
CAS Number
1627580-64-6
Purity
99% · batch-tested
Description
MOTS-c is a mitochondrial-derived peptide studied for AMPK, glucose metabolism, stress adaptation and exercise-response signalling.
Research Focus
Metabolic flexibility, insulin-sensitivity, mitochondrial and exercise-adaptation research.
Suggested Use
Reference plan: 1 mg aliquots, Monday to Friday in a defined 12-week research block.
Doses per Vial
10 x 1 mg reference aliquots.
Concentration
1 mg per reference aliquot from a 10 mg vial.
Notes
Emerging evidence is largely mechanistic and preclinical; keep customer copy cautious.
Monthly Ranking
#9 most popular research peptide
MOTS-c carries 267 indexed publications, 4 registered trials, 4,712 monthly readers on Wikipedia. Research activity sits at 55 papers in the past twelve months against 46 the year before.
Why It's Searched
Mitochondrial and metabolism-adjacent searches from more advanced shoppers.
Evidence Standing
267 papers, 55 this year · 4 trials · 4,712 readers (-6%) · B tier
MOTS-c AustraliaMOTS-c peptidemitochondrial peptide researchmetabolism peptide research
Updated 2 August 2026
Prepared with care, sealed under argon, and stored at 2–8°C until dispatch. Reconstitute with Bacteriostatic Water before use. Full preparation and storage guidance included with your order.
Independent Research
Evidence Overview on reptides.coIndependent third-party research on reptides.co — not affiliated with Polaris Research. Research reference only, not medical advice.
MOTS-c 10mg arrives sealed and research-ready, with a written preparation and storage card in every order. Prepare and store it as set out below, and use the reconstitution calculator to work out your concentration and draw volume before you begin.
Step 01
On arrival
Your MOTS-c 10mg vial arrives securely packaged. Refrigerate it sealed at 2–8°C until you are ready to prepare.
Step 02
Prepare gently
Add Bacteriostatic Water slowly against the vial wall, then swirl gently. Never shake.
Step 03
Store correctly
Once prepared, aliquot and freeze at −20°C. Avoid repeated freeze–thaw cycles.
4.7
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- What is MOTS-c?
- MOTS-c is a mitochondrial-derived peptide studied for AMPK signalling, glucose metabolism, and metabolic-signalling research. It belongs to the Weight & Metabolism family and is studied for its signalling activity in mitochondrial and metabolic research. It is supplied as a lyophilised powder for in-vitro laboratory research purposes only, not for human use.
- Can I buy MOTS-c at Chemist Warehouse in Australia?
- No. MOTS-c is not available at retail pharmacies like Chemist Warehouse, Priceline, or any Australian pharmacy. It is a research compound not approved for human use by the TGA. Polaris Research supplies MOTS-c exclusively as a lyophilised powder for in-vitro laboratory research.
- Can Australian compounding pharmacies supply MOTS-c?
- MOTS-c is not an approved commercial medicine and is not available as a compounded prescription product through Australian pharmacies. Polaris Research supplies research-grade MOTS-c for lawful in-vitro laboratory research only, with independently verified batch certificates on every order.
- Where to buy MOTS-c in Australia?
- MOTS-c is available through Polaris Research with fast domestic Express Delivery to all Australian states and territories. Every vial is dispatched from within Australia, no customs delays, no international freight uncertainty. Each batch is independently third-party tested to ≥98% purity, with the Certificate of Analysis verifiable on our batch verification page.
- What is the cost of MOTS-c in Australia?
- MOTS-c 10mg is available from Polaris Research at $109 per vial with Free Express Delivery Australia-wide and independently verified batch documentation. See the product page for current pricing and any available larger formats.
- How to get MOTS-c online in Australia?
- Add MOTS-c 10mg to your cart on the Polaris Research website and complete checkout. All orders are fulfilled domestically and shipped with Australia Post Express tracking to any address across Australia. A 24-hour payment reservation holds your stock from the moment you order.
- How do I reconstitute the vial?
- Reconstitute by adding Bacteriostatic Water slowly down the inside wall of the vial, never directly onto the powder. Swirl gently to dissolve; do not shake. Once reconstituted, keep the solution refrigerated and avoid repeated freeze-thaw cycles. For a step-by-step walkthrough, see our Peptide Reconstitution Guide.
- How should I store it?
- Store the unopened lyophilised vial refrigerated at 2–8°C, kept dark and upright. Once reconstituted, keep the solution refrigerated and use it within a few weeks. Never re-freeze a reconstituted solution, ice crystals damage the compound. A clear, particle-free liquid is the sign of a clean reconstitution.
- How is MOTS-c 10mg verified?
- Every batch of MOTS-c 10mg is independently third-party tested to 99% purity by HPLC and mass spectrometry at an accredited laboratory. The batch certificate ships with your order and can be verified on our batch verification page using the batch number on the vial label. We never ship a vial without a matching certificate.
- Is MOTS-c 10mg shipped Australia-wide?
- Yes, shipping is always free: every order includes free Australia Post Express Delivery, Australia-wide, with tracking. Orders dispatch within 2 business days of confirmed payment, with most dispatched within 24 hours (weekends excluded). A 24-hour payment reservation holds your stock from the moment you order.
- Can I pay with Afterpay or another buy now pay later plan?
- Yes. Afterpay, Zip and Klarna are all offered on Stripe's secure payment page at checkout, alongside card, Apple Pay and Google Pay. Choose the Afterpay, Card & Apple Pay option, then pick your provider on the payment page, where the plan is shown and approved before your order is confirmed. We add no surcharge for paying in instalments, and the price is the same as paying in full. Your order then ships on the normal schedule, most within 24 hours of confirmed payment, so there is no wait for the instalments to finish. Approval and the amount available to you are the provider's decision, not ours. If you would rather pay in full, PayID / Osko bank transfer and PayPal are both offered at checkout.
Educational and product-logistics information only. Nothing here is medical advice or a therapeutic claim.
Pairs Well With
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Related Reading
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Read →Also Searched As·MOTS-c is also searched as MOTS-c, MOTSc, MOTS c, Mitochondrial ORF peptide, MOTS-c peptide.
Research File
SteadyWhat has been published on MOTS-c
MOTS-c appears in 267 indexed publications going back to 2015, including 55 in the past twelve months. 4 registered trials appear on ClinicalTrials.gov.
267
Indexed publications
55
Past 12 months
4
Registered trials
4,712
Monthly readers, down 6%
20152026
Publications per year. The final bar is the current year, still in progress.
| 2015 | 4 |
|---|---|
| 2016 | 3 |
| 2017 | 3 |
| 2018 | 13 |
| 2019 | 22 |
| 2020 | 14 |
| 2021 | 31 |
| 2022 | 22 |
| 2023 | 35 |
| 2024 | 32 |
| 2025 | 46 |
| 2026 | 41 |
Read the full MOTS-c research fileCounts from Europe PMC and ClinicalTrials.gov, refreshed weekly. Reported as a record of what exists, not as evidence of any effect.