NAD+
NAD+ appears in 3,154 indexed publications going back to 2017, including 369 in the past twelve months. 211 registered trials appear on ClinicalTrials.gov, 2 with Australian sites.
On This Figure
NAD+ is a coenzyme present in every living cell, so this figure describes an entire field of metabolic research rather than one compound.
Publication history
How much work has been indexed each year, from Europe PMC. Momentum is measured over a trailing twelve months rather than calendar years, so a partial current year never reads as a decline.
Publications per year. The final bar is the current year, still in progress.
| 2015 | 0 |
|---|---|
| 2016 | 0 |
| 2017 | 1 |
| 2018 | 4 |
| 2019 | 16 |
| 2020 | 23 |
| 2021 | 45 |
| 2022 | 101 |
| 2023 | 117 |
| 2024 | 190 |
| 2025 | 225 |
| 2026 | 276 |
Who is looking it up
Monthly readers of the NAD+ article on English Wikipedia. An independent measure of curiosity, which often moves quite differently from the evidence.
The registered pipeline
2 trials have a registered Australian site.
Phase distribution across the most recently updated registered trials.
- Recruiting·Not applicable
Scott Silveira · estimated completion 2026-12-30
- Not yet recruiting·Phase 2
PEDIatric Cardiac Dysfunction Treated With Injectable Nicotinamide Adenine Dinucleotide
Beijing Children's Hospital · estimated completion 2028-04-01
- Recruiting·Phase 2
Suzhou Suncadia Biopharmaceuticals Co., Ltd. · estimated completion 2027-12
- Not yet recruiting·Phase 1
NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome
Brigham and Women's Hospital · estimated completion 2028-02-29
- Enrolling by invitation·Not applicable
NAD Supplementation in Parkinson's Disease
University of Oklahoma · estimated completion 2027-07
- Not yet recruiting·Not applicable
NAD Supplementation to Reduce the Incidence of Cardiac Surgery Associated Acute Kidney Injury
Beth Israel Deaconess Medical Center · estimated completion 2028-10-01
Most recent work
The newest indexed records mentioning NAD+, listed by publication date. Titles are shown as published and link to their source. Inclusion here is a record of what exists, not a judgement of what it shows.
- 2026-09-22·Synthetic and systems biotechnology
Zhao R, Li C, Xu C et al.
- 2026-10-09·Experimental neurology
Asimakopoulos T, Kokkinou E, Faze T et al.
- 2026-06-27·Bioactive materials
Jiang J, Chen J, Wang X et al.
- 2026-02-12·Pharmaceutical science advances
Shi L, Huang X, Han X et al.
- 2026-04-16·Renal failure
Zhang Y, Wang Y, Qiao Y et al.
- 2026-03-10·Gut microbes
Huang J, Qin Q, Li X et al.
- 2026-09-19·Toxicology and applied pharmacology
Mo'men M, Saber S, Amer AE et al.
- 2026-08-02·Theriogenology
El-Sheikh M, Mesalam A, Lee SH et al.
NAD+ available from Polaris Research
Supplied as research materials for laboratory use. Free express delivery Australia wide.
Sources
Publication data from Europe PMC. Clinical trial data from ClinicalTrials.gov, U.S. National Library of Medicine. Public attention from Wikimedia pageview data. Evidence grades from reptides.co. We report counts and dates from these sources and link every record to its origin, we do not summarise findings. Last synced 2026-10-25.